Pure-ific, Corp.
Overview
This division of Provectus is focused on over-the-counter (OTC) consumer products. It was created to produce immediate revenues for the company to help support its core development programs in oncology and dermatology. Pure-ific Corp. is introducing retail products for three areas of skin care:

• An effective and long-lasting antibacterial spray for hands and surfaces
• A product to provide comfort to users of disposable gloves
• A novel treatment for mild-to-moderate level acne sufferers.

Pure-ific Corp.’s over-the-counter products are designed to be safer and more specific than competing products. Patent applications have been filed for specific uses.

All Provectus OTC products have these factors in common:

Further Details on OTC Products
Pure-ific™ Antibacterial hand and surface spray
The emergence of new diseases, such as SARS, has created a growing demand for anti-microbial agents for hands and surfaces. Pure-ific™ Antibacterial hand spray is being introduced into the retail market in the latter half of 2004 to meet this demand.

Most antibacterial agents are quick-drying gels. As a spray, Pure-ific™ is dual purpose, appropriate both for hands and hard surfaces, such as toilet seats. Pure-ificTM immediately kills up to 99.9% of bacteria found on skin and prevents re-growth for six hours. In the laboratory, Pure-ific™ has been shown to kill over 99.9 percent of a feline Corona virus, the same kind of virus associated with SARS.

Markets
Hand sanitizers comprise a $100 million market. Antibacterial sprays, such as Lysol, represent a $1.2 billion market.

GloveAid™ and GloveAid™ MC Moisturing Conditioner
Disposable gloves have become ubiquitous in many professions. Along with medical workers and food handlers, airport security personnel, police and fire personnel, mail handlers, and others are now donning disposable gloves. As a result, many are experiencing chronic skin irritation. GloveAid™ is aimed at this market.
Chronic skin irritation associated with prolonged glove use is typically treated as an allergy. However, company scientists have isolated a bacterium that proliferates inside workers’ gloves, where perspiration creates a warm, wet environment conducive to bacterial growth. GloveAid™ is a hand cream that combines an antiperspirant with an antibacterial agent to control excessive perspiration. It thus treats the cause, rather than the symptoms, of the problem.

Market
The worldwide market for disposable gloves is more than $3 billion. As usage continues to mount, it is anticipated that corresponding amounts will be spent on hand-care products.

Key features of GloveAid™

Second-stage OTC products
Second-stage products will target acne, eczema, and mild to moderate psoriasis. The company also plans to develop specialized hand and foot antiperspirants for athletic use. Like GloveAid™, these products are designed to alter the skin environment to control microbial growth.

Pure-Stick™
Pure-Stick™ is an acne treatment. Acne results from an overproduction of sebum and other fluids in the skin, which can plug sweat glands and ducts, providing an ideal environment for proliferation of normally benign bacteria.

Pure-Stick™ is a non-toxic, topical agent that checks the production of sebum and sweat while damping skin pathogens associated with acne. Pure-Stick™ can be used both as a remedy and a preventative for acne.

Market
Acne affects approximately 17 million people in the United States. Combined sales of OTC products for mild to moderate cases topped $800 million in the year 2000.